Department for Science, Innovation and Technology (Office for Life Sciences)

Life Sciences Innovative Manufacturing Fund (LSIMF)

Capital grants from the Office for Life Sciences for UK manufacturing investments in human medicines, medical diagnostics and MedTech that increase UK health resilience and create high-wage, high-skilled jobs. Single-company (or same-group) projects with eligible costs of at least £8m can apply; the maximum grant is 25% of project costs, typically 10-20%. Expressions of Interest are taken at any time and assessed in quarterly rounds, with Round 9 closing at 12pm on 13 November 2026.

You could get
£1,000,000 – £130,000,000
no fixed round
Deadline
Rolling
apply any time
Effort
Heavy
budgets, references, often several stages

Who can apply

  • UK-registered companies, or UK-registered establishments with at least one UK-registered company in their group, that are wholly private sector businesses and act as a product developer, contract development manufacturing organisation or generics manufacturer
  • Previous manufacturing grant recipients can apply for a different project
  • Applicants must provide two years of audited accounts (company and/or parent), or show the rest of the project funding is available, and may be asked for evidence of a track record in manufacturing medicines or medical devices or of developing a product for commercial scale-up
  • The project must be in the UK, primarily capital, have total eligible costs of at least £8m, be a single company investment or joint investment within one company group, and need the grant to proceed (otherwise it would not go ahead, be smaller, go overseas or be delayed 3+ years)
  • Facilities must work to GMP; device and diagnostics makers must meet or intend to meet the Medical Devices Regulations 2002
  • Northern Ireland projects in scope of the Windsor Framework fall under EU State aid rules

What it funds

Primarily capital investment projects in the UK for the manufacture of:

  • Human medicines, including active pharmaceutical ingredients (API) / drug substance and finished product / drug product
  • Medical diagnostics, for both disease identification and monitoring
  • MedTech products: all types of medical devices related to human health
  • MHRA-licensed medicines, MHRA-registered medical and diagnostic devices, and products in development intended for UK approval and commercial scale-up (e.g. manufacturing for clinical trials or investigational studies)

Eligible costs include capital, R&D and skills/training expenditure, excluding operational expenditure. The maximum intervention rate is 25% of project costs, typically 10-20%.

What it will not fund

  • Veterinary medicine
  • Herbal medicines
  • Nutritional supplements or vitamins
  • Raw ingredients (e.g. solvents, buffers and cleaning agents)
  • Production of single-use consumables not integrated into a larger product (e.g. syringes made independently from diagnostic kits)
  • Secondary packaging (e.g. package inserts, labelling and boxes)
  • Partnerships between independent companies or other types of organisations
  • Operational expenditure
  • Projects that would proceed without the grant

How to apply

  1. Submit an Expression of Interest (project summary) through the Find a Grant page at any time; to be considered in Round 9 it must arrive by 12pm on 13 November 2026
  2. If the EOI is eligible you are invited to complete Application Form 1 on the project's health resilience benefits, assessed by cross-government officials
  3. Give a short presentation and Q&A to a panel of independent manufacturing experts
  4. If successful, complete Application Form 2 (eligibility, company and project details, financial information, markets, economic impacts and risks) with supporting documentation
  5. Due diligence on value for money, subsidy control, the no-grant scenario, deliverability, jobs and financing

EOIs after a round's deadline go into the next quarterly round; rounds continue until all funding is allocated, and the scheme is reviewed annually so criteria and windows may change. Queries to LSIMF@officeforlifesciences.gov.uk.

Have ready

  • Expression of Interest form
  • Application Form 1
  • Application Form 2
  • Two years of audited accounts for the applicant company and/or parent entity (or evidence the remaining project funding is available)

Further evidence of financial position, eligibility and project viability is requested at Application Form 2 and due diligence.

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